Coverart for item
The Resource Fatal flaws : how a misfolded protein baffled scientists and changed the way we look at the brain, Jay Ingram

Fatal flaws : how a misfolded protein baffled scientists and changed the way we look at the brain, Jay Ingram

Label
Fatal flaws : how a misfolded protein baffled scientists and changed the way we look at the brain
Title
Fatal flaws
Title remainder
how a misfolded protein baffled scientists and changed the way we look at the brain
Statement of responsibility
Jay Ingram
Creator
Subject
Genre
Language
eng
Summary
"Discovered and identified as the cause of mad cow disease only three decades ago, the prion is a protein molecule that, when misshapen in the brain, becomes fatal. Novel and controversial, prions have provoked a scientific revolution. They challenge the very foundations of biology: A disease-causing entity with no genetic material at all? A molecule capable of infecting, multiplying, and killing? This book recounts the birth of prion science and the imaginative detective work scientists have undertaken as they struggle to find the answers to devastating brain diseases from mad cow and Creutzfeld-Jakob disease to Parkinson's, Alzheimer's, Lou Gehrig's, and others."--Provided by the publisher
Summary
A look at prions, a misfolded protein that could be the key to treating devastating brain diseases but has created controversy among top scientists.
Award
Science in Society Book Award (Canadian Science Writers' Association), for Adult Nonfiction, 2012.
http://library.link/vocab/ext/novelist/bookUI
10126636
Cataloging source
DNLM/DLC
http://library.link/vocab/creatorName
Ingram, Jay
Dewey number
616.8/3
Illustrations
illustrations
Index
index present
LC call number
QR201.P737
LC item number
I537 2013
Literary form
non fiction
Nature of contents
bibliography
NLM call number
WL 301
http://library.link/vocab/resourcePreferred
True
http://library.link/vocab/subjectName
  • Prion diseases
  • Slow virus diseases
  • Central nervous system
  • Prion diseases
  • Prions
  • Prion Diseases
  • Prion Diseases
  • Prions
  • Prions
Target audience
adult
http://bibfra.me/vocab/lite/titleRemainder
how a misfolded protein baffled scientists and changed the way we look at the brain
Label
Fatal flaws : how a misfolded protein baffled scientists and changed the way we look at the brain, Jay Ingram
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
The mystery of kuru : a disease like no other -- Barflies and flatworms : how speculation and pure chance advance a new science -- Cannibalism : an answer guaranteed to stir things up -- Igor and Bill : the discoveries that bring kuru to world attention -- The life of a cell : a miraculous, and often precarious, complexity -- The death of a cell : by subterfuge, piracy or out-and-out assault -- When is a virus not a virus? : when a disease-causing agent reproduces without genes -- Creutzfeldt-Jakob disease : waking up to the potential of a devastating affliction -- Magnificent molecules : the proteins that make life possible -- Protein origami : building the gothic cathedrals of life -- Stanley Prusiner's heresy : an infectious agent that's a protein and nothing but -- An infectious idea : the campaign for the minds of researchers -- A portrait of the prion : and the experiments that point to their role in the human brain -- Mad cow disease : the uncertain ground where politics and science intersect -- Mad cow in humans : no barrier after all -- The Americas : mad mink, then cows -- Into the wild : deer, elk, moose and caribou -- Origins : attempting to find where prions come from -- Cats but not dogs : when prions jump the species barrier -- Alzheimer's disease : plaques and tangles but so far no prions -- Parkinson's disease : looking more and more like a prion disease -- Lou Gehrig's disease : the emerging picture of a prion-like process in ALS -- Chronic traumatic encephalopathy : the athletes' plague -- And in the end...
Control code
952224
Dimensions
22 cm
Extent
viii, 282 pages
Isbn
9780300189896
Lccn
2012042874
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
System control number
  • (Sirsi) i9780300189896
  • (DNLM)101594404
Label
Fatal flaws : how a misfolded protein baffled scientists and changed the way we look at the brain, Jay Ingram
Publication
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
The mystery of kuru : a disease like no other -- Barflies and flatworms : how speculation and pure chance advance a new science -- Cannibalism : an answer guaranteed to stir things up -- Igor and Bill : the discoveries that bring kuru to world attention -- The life of a cell : a miraculous, and often precarious, complexity -- The death of a cell : by subterfuge, piracy or out-and-out assault -- When is a virus not a virus? : when a disease-causing agent reproduces without genes -- Creutzfeldt-Jakob disease : waking up to the potential of a devastating affliction -- Magnificent molecules : the proteins that make life possible -- Protein origami : building the gothic cathedrals of life -- Stanley Prusiner's heresy : an infectious agent that's a protein and nothing but -- An infectious idea : the campaign for the minds of researchers -- A portrait of the prion : and the experiments that point to their role in the human brain -- Mad cow disease : the uncertain ground where politics and science intersect -- Mad cow in humans : no barrier after all -- The Americas : mad mink, then cows -- Into the wild : deer, elk, moose and caribou -- Origins : attempting to find where prions come from -- Cats but not dogs : when prions jump the species barrier -- Alzheimer's disease : plaques and tangles but so far no prions -- Parkinson's disease : looking more and more like a prion disease -- Lou Gehrig's disease : the emerging picture of a prion-like process in ALS -- Chronic traumatic encephalopathy : the athletes' plague -- And in the end...
Control code
952224
Dimensions
22 cm
Extent
viii, 282 pages
Isbn
9780300189896
Lccn
2012042874
Media category
unmediated
Media MARC source
rdamedia
Media type code
  • n
Other physical details
illustrations
System control number
  • (Sirsi) i9780300189896
  • (DNLM)101594404

Library Locations

    • Central LibraryBorrow it
      710 W. Cesar Chavez St, Austin, TX, 78701, US
      30.271302100000 -97.746016800000
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